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The aim is to study and compare the processes of regeneration of bone tissue in animals while grafting titanium nickelide granules in bone cavities and free plastics in experiment. Methods. Two methods of bone grafting were experimentally reproduced to assess the speed of regeneration of bone tissue of dogs’. The first is traditional method with bone crumbs, and the second one of filling the bone cavity with fine-grain titanium nickelide. The last-named has been developed lately. In the first group consisting of 25 dogs, granules of porous titanium nickelide were placed in the formed cavity of shin bone epiphysis. In the second (control) group (consisting of 10 dogs), bone crumbs were introduced into the cavity of the shin bone. Results. The experiment showed that fine-grain titanium nickelide use for grafting bone cavity in comparison with bone crumbs demonstrated the formation of bone organo-typical regenerate 3 months faster. Conclusions. Fine-grain titanium nickelide is a promising material and can be used in the pathology of the skeleton.

The use of fine - grained nickelide titanium, in the experiment, for the pathology of the musculoskeletal system.