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We have studied the morphology of buccal epithelial cells of young smokers with up to 5 years of smoking history. The biomaterial of smokers has shown a significant decrease in the fraction of norm cells and a two-fold increase in the proportion of different morphological abnormalities of cells (tst=0,1%, Р=0,001). In buccal epithelial cells of smokers, cells with cytogenetic disorders (tst=0,1%, Р=0,001) are observed 1,5 times more frequently; disorders of cell proliferation processes and cells with the initial signs of the nucleus destruction (tst=1%, Р=0,01) occur more than twice often. Cells with the signs of complete destruction of the nucleus in smokers are reliably characterized by a significant increase in the number of cells with karyolysis (tst=1%, Р=0,01). The index of accumulation of cytogenetic violations in smokers is calculated.

vestnik moskovskogo gosudarstvennogo oblastnogo universiteta. seriâ: estestvennye nauki/vestnik moskovskogo gosudarstvennogo oblastnogo universiteta. seriâ estestvennye nauki

CYTOMORPHOLOGICAL FEATURES OF BUCCAL EPITHELIAL CELLSIN SMOKING YOUTHS