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Background: Overweight and obesity are major risk factors for many chronic diseases in modern societies. A retrospective follow-up study showed an advantage of weight reduction diet (WRD) to fasting therapy concerning long-term weight loss. Objective: Prospective comparison of WRD to fasting therapy concerning long-term weight loss. Methods: From 08/2007 to 02/2009 90 patients with overweight or obesity were observed with a follow-up period of 6 months, who received either a fasting therapy or a WRD in the context of naturopathic complex in-patient treatment including physical activity. Results: During the in-patient treatment the fasting patients loosed significantly more weight than the WRD patients, but regained weight during the follow-up, while the weight loss of the WRD patients persisted. 32% of the fasting and 81% of the WRD patients achieved a 5% weight loss after 6 months. Total and LDL-cholesterol were significantly more reduced, controlled eating habits, physical leisure activity and tendentially physical quality of life increased more after 6 months in the WRD group, while the systolic blood pressure declined more in the fasting patients. Conclusion: Weight loss and improvement of obesity-associated parameters were long-term significantly inferior in fasting patients compared to patients treated with a WRD. The reduced success of the fasting patients is probably caused by the minor lifestyle modification.

Fasting Therapy versus Standard Weight Reduction Diet Combined with Naturopathic Complex Treatment in Patients with Overweight and Obesity