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Human physiology and pathophysiology of diseases have been proved to show rhythmic variation in response to temporal factors. This behavior is intertwined in field of clinical physiology in form of chronomedicine and chronotherapy for the better outcomes of treatment. Ayurveda scholars have also described rhythmic variation in biological entities like Dosha , Agni , Bala , presentation of diseases in relation to diurnal, meal intake and seasonal factors. They have well documented different domain of drug i.e. collection of drug, preparation of medicine, intervention of therapeutic procedures and administration of medicine in accordance to variation in biological entities and time. This article is aimed to summarize all these documented observations of Ayurveda regarding chronomedicine and chronotherapy and discuss in view of contemporary sciences, so that it can be utilized by the researchers of this field to generate evidence based data and may be applied by the physician for the better prognosis and management of the disease.

A Scientific Exploration on Concept of Chronomedicine and Chronotherapy in Ayurveda