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FLOW AND PRESSURE MEASUREMENT USING PHASECONTRAST MRI: EXPERIMENTS IN STENOTIC PHANTOM MODELS Iman Khodarahmi May 29, 2012 Peripheral Arterial Disease (PAD) is a progressive atherosclerotic disorder which is defined as any pathologic process obstructing the blood flow of the arteries supplying the lower extremities. Moderate stenoses mayor may not be hemodynamically significant, and intravascular pressure measurements have been recommended to evaluate whether these lesions are clinically significant. Phase-contrast MRI (PC-MRI) provides a powerful and non-invasive method to acquire spatially registered blood velocity. The velocity field, then, can be used to derive other clinically useful hemodynamic parameters, such as blood flow and blood pressure gradients. Herein, a series of detailed experiments are reported for the validation of MR measurements of steady and pulsatile flows with stereoscopic particle image velocimetry (SPIV).

Flow and pressure measurement using phase-contrast MRI : experiments in stenotic phantom models.