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SIGNIFICANCE OF ORIENTATION AND DETERMINATION OF CUMMULATIVE DAMAGE MEASURES DURING CYCLIC TESTING OF HUMAN THORACOLUMBAR SPINE Sai Vikas Valla July 18,2006 Determining the mechanical properties of the spme IS a significant step in understanding the behavior of the spine under normal conditions. Although a limited amount of data for cyclic loading is currently available, the tests are not completely documented and the loads, spine segment positioning, and frequency are not representative of those typically found during normall activities. The purpose of this study is to develop an understanding of the relationship between loads and the development of fatigue failure in thoracolumbar motion segments. Motion segments separated from human cadaveric spine were tested in two series. Compression series applied a pure compression load quasi-statically in the neutral position. The load was increased and the specimen was observed to determine failure. Motion segments were also tested without orientation (axially aligned). The difference of failure stress was analyzed to see the influence of spine segment positioning on the mechanical properties of the spine. 50% of the failure stress from neutrally aligned motion segments was used to define the loading for cyclic compression tests. Flexion series of testing applied a maximum bending moment on the motion segment in neutral

Significance of orientation and determination of cummulative damage measures during cyclic testing of human thoracolumbar spine.