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The work outlined in this thesis expanded on previous work to improve a thin-film microfabricated electrode array intended for cardiac electrophysiology studies. A thin layer of silver was added in between titanium and platinum electrical trace layers to reduce electrode resistance. A 200 nm layer of silver decreased electrode resistance by an order of magnitude. In addition, a new high quality signal conditioning board was developed using precision operational amplifiers from Texas Instruments. Both new sensor and board design were verified together through in vivo studies using rabbit, goat, and dog hearts. TABLE OF CONTENTS APPROVAL PAGE ACKNOWLEDGEMENTS ABSTRACT TABLE OF CONTENTS LIST OF TABLES LIST OF FIGURES

An improved thin-film microelectrode array and signal conditioning board for measuring cardiac surface potentials.