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This study deals with the analysis of wavefront aberrations that occur in the image owing to curvature variations in the human eye cornea. The analy- sis is based on the Liou-Brennan human eye model. The surface curvature and wavefront aberrations are described using Zernike polynomials. Our approach involves evaluating parameters of the distorting system's transfer function and measuring the expansion coefficients based on pattern recognition methods. Constructing a feature space of medical images enables the evaluation of aber- rations in the eye optical system to be performed. Our study aims to address a problem of the differential diagnosis of the human eye optical structures through analyzing higher-order aberrations of the focusing system. The human eye has been known to provide the major proportion of information about the world (1-4). Impaired eye-vision deteriorates the quality of life. The immense experience science has gained in the treatment of eye diseases indicates that a key culprit is age-related changes in the eye optics, which can be evaluated based on wave aberrations. Higher-order (higher than astigmatism-related) aberrations cannot be corrected for and detected by standard optical techniques, while patients may com- plain of an impaired vision. At the same time, the eye may be affected by optical- system-unrelated diseases which can also have a potentially adverse effect on the vision. If higher-order aberrations and nonoptical abnormalities occur simultaneously

EVALUATION OF ABERRATIONS IN THE OPTICAL SYSTEM OF THE HUMAN EYE BASED ON THE SPATIAL SPECTRUM OF A DIAGNOSTIC IMAGE