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Over the past 30 years, diseases in the hoof area in cows are a very serious and actual problem for all dairy farming. During the treatment of purulo-necrotic diseases of fingers, particular importance should be given to the search of new means of facilitating the cleansing of the wound surface from purulent exudate, early elimination of inflammation and a more rapid formation of healthy granulation tissue in the wound and quicken the transition of the inflammatorydystrophic phase (hydration) in the regenerative phase (dehydration). This article shows the results of histological studies of selected tissue samples with puruo-necrotic ulcerative lesions in the hoof area against the complex therapy. The research was conducted on the basis of LLC PSK “Krasnaya Zvezda” of the Ulyanovsk region, on cows suffering from purulo-necrotic ulcers in the hoof area. The material for histological studies was selected after mechanical treatment of the limbs from the areas of affected soft tissues in the hoof area before treatment, on the 7th and 14th days, with subsequent fixation in 10 ... 12% formalin. The sections were colored using hematoxylin and eosin and Van Gizon staining. During conducted research it is established that when using biologically active Diotevin sorption preparation in complex treatment of orthopedic ill cows on histological level revealed weak evidence of the inflammatory process, changes of angiogeneses structure of granulation tissue in the form of increased vessel density, capillary type and number of fibroblastic cells with further proliferation of epithelial cells in the dermis with recovery of epidermis with signs of hyperkeratosis.

HISTOLOGICAL CHARACTERISTICS OF REPARATIVE PROCESSES OF THE SOFT TISSUES IN THE HOOVES IN ORTHOPAEDIC COWS