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Background: Oropharyngeal cancers are most commonly observed cancers in Indian population.Oropharyngeal cancers have a poor prognosis. A histopathological study of lesions will give the exactcause and helps in initiation of optimal therapy at the earliest.Settings and design: Prospective studyAims: To study the histopathological changes in tumour and tumour like lesions of oral cavity andoropharynxMaterial and Methods: A prospective study was carried out in patients of oral cavity and oropharynxlesions. Total 100 biopsies and resected specimens were studied. Data included sociodemographic data,clinical features and histopathological diagnosis of the specimen.Statistical analysis used: Appropriate statistical testsResults and Conclusion: In our study we observed 10% tumor like lesions, 4% benign lesions,4% premalignant lesions and 63% malignant lesions. Mucocele was the commonest tumor like lesion.Squamous cell carcinoma was the most common malignant lesion in our study seen in 95.2% cases. Out of60 Squamous cell carcinoma cases, 11.6% had lymph node metastases and 3.3% showed lymphovascularinvasion. In TNM staging of 14 cases who underwent resection with modified radical neck dissection,maximum number of cases belonged to Stage II (35.71%) and Stage IV (35.71%).Keywords: Histopathology, Oral cavity, Oropharynx, Tumor, Tumorlike.

Histopathological spectrum of tumor and tumor like lesions of oral cavity and oropharynx in tertiary care hospital