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Soft tissue sarcomas account for less than 1% of overall human burden of malignant tumors.Our study was conducted in a tertiary care hospital in konaseema region to identify various histologicalpatterns of the soft tissue tumors along with their relation to age, sex and site.Materials and Methods: 215 cases of soft tissue tumors were analysed both retrospectively andprospectively for two years during January 2015 to January 2017. A careful histopathological examinationwas done with clinical correlation.Results: In a span of two years, we received 215 soft tissue tumors, 179 cases (83.2%) were benign innature, 18 (8.3%) cases were of intermediate grade malignancy and 18 (8.3%) were malignant. Males wereaffected more than females. The most common site was lower extremities.Conclusion: A vigilant Histopathological examination using Hematoxylin and Eosin stain (H&E) withclinical correlation is still an important tool and gold standard in diagnosing various patterns of soft tissuetumors.Keywords: Soft tissue sarcoma, Benign, Malignant, Hematoxylin and Eosin stain.

Spectrum of soft tissue tumors: A two year clinicopathological study at tertiary level hospital