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Kidneys are vital organ for multiple function in the body. Thereby kidney can be involved in various pathological processes. Nephrectomy is the treatment of choice in extreme and untreatable conditions including malignancies. Aims and Objectives: In this study we aim to analyse the nephrectomy specimen received in terms of the various epidemiological factors and their clinico-histopathological correlation. The study also aims to give an account of currect trend of nephrectomy in the study population. Materials and Methods: This is three year prospective and retrospective analysis of the consecutive nephrectomy specimen received in department of pathology with emphasis on epidemiological and clinic-pathological correlation. Results: A total of 48 nephrectomy specimen received during the study period, 28(58%) were male and 20(42%) were females. We found that 40% of the cases constituted that of chronic pyelonephritis with or without end stage renal disease while renal cell carcinoma of clear cell type constituted 17% of the cases. Conclusion: This study concludes that non neoplastic indications for nephrectomy constitute the major burden in our study population. These conditions if diagnosed in advance can be treated and nephrectomy can be avoided. Introduction Kidneys are vital organ for multiple function in the body. From Apart from excretory function their function ranges from maintaing the acid base balance in the body to as important as maintain the required blood pressure. As can be expected from the functions involved, kidney can be associated with various pathological processes. The patients often present with various symptoms including loin pain, hematuria, mass per abdomen and various radiological investigations signifying reduced renal functioning. Although most of the pathologies can be treated on medical basis alone, nephrectomy is done in extreme and untreatable conditions. Nephrectomy is the treatment of choice in renal cell carcinomas. In this study we aim to analyse the nephrectomy specimen received in terms of various epidemiological factors and their clinico-histopathological correlation. The study also aims to give an account of current trend of nephrectomy in the study population. Materials and Methods This is three year prospective and retrospective analysis of the all the consecutive nephrectomy specimen received in department of pathology during the specified duration from 2015-2018 of our institute. Ours is multispeciality tertiary care teaching institute located in Pune, Maharashtra, India. A total of 48 nephrectomy specimens were received during this period. The study included cases of one year in retrospective collection of data from the departmental records and two years of prospective collection of information as and when the nephrectomy specimen were received in the department of pathology. The specimens were sent to histopathology section in 10% formalin. Patient particulars were recorded in detail on prepared proformas, which included age, sex, and clinical findings, investigations such as X-ray, USG, DTPA and other relevant investigations were also noted. The diagnosis and impression given after the gross and histopathological examination were recorded for each case in both prospective and retrospective data collection. The details of each case were matched with the corresponding histopathology results. The data was then studied in detail with emphasis on epidemiological and clinic-pathological correlation. Analysis for the age wise, sex wise distribution of cases for each lesion with mean age for each lesion was recorded. The study aims to present the current trend of nephrectomy with pathological correlation in the study population. Article Info Received: 12th January, 2019 Accepted: 9th March, 2019 Published Online: 9th August, 2019

Current nephrectomy scenario with pathological correlation in a tertiary care centre - A three year study