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Introduction: Prevention of postoperative pain can be achieved by effective blockade of noxious stimuli generated during surgery that is after central sensitization. Preventive analgesia or antinociceptive treatment started before surgery in order to prevent central sensitization and limit the subsequent pain experience.1Aim and Objective: The aim of the study was to evaluate the role of NSAIDs as preemptive analgesia in controlling pain and swelling after gingivectomy.Materials and Methods: total of 60 patients were randomly divided into 3 groups, Group A: Tab Aceclofenac 100mg given 30 minutes before gingivectomy, Group B: Tab Ibuprofen 400mg and in Group C: Placebo given to the patients 30 minutes before gingivectomy procedure. Pain intensity were recorded at 6hr, 12hrs, 24hrs, day 2 and day 3 post gingivectomy. Swelling and No. of rescue analgesic taken by the patient recorded at day 1, day 2 and day 3 after gingivectomy.Result: The result showed that postoperative pain and swelling reduction was better with Aceclofenac followed by Ibuprofen then Placebo. The distribution of pain reduction was statistically significant at 6hr postgingivectomy.Conclusion: A preoperative single dose of anti-inflammatory drugs (NSAIDs) can regulate the release of inflammatory mediators and reduce the amount of pain and swelling during postoperative period.Keywords: Nonsteroidal anti-inflammatory drugs, Chemical mediators, Gingivectomy, Preemptive analgesia, Visual analog scale.

Comparative study for effectiveness of preemptive analgesia on postoperative pain and swelling following gingivectomy