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Purpose: To compare the outcomes of treatment of primary chalazion with intralesional Triamcinolone Acetonide (TA) and Incision & Curettage(I&C) in patients with failed conservative treatment. Materials and Methods Study Design: Prospective randomized study Place and Duration: The study was conducted from November 2017 to January 2019 in The Department of Ophthalmology, Narayana medical college, and Hospital, Nellore. Methodology: 40 patients with primary chalazia who, after failed conservative treatment were randomized to either intralesional TA injection (4 mg) or I&C performed under local anesthesia. Preoperative photograph of the lesion was taken. Complete resolution was considered as lesion regression of 95% to 100%. Treatment was considered a failure if no resolution was achieved after the first attempted I&C or TA injection. Lesion resolution measured as 95% to 100% regression. Results: Out of 40 patients, 20 were randomized to I&C and 20 to TA injection group. Complete resolution was achieved in 16 cases in the I&C group and 17cases in TA group. The average time of resolution in TA group was four days. No significant complications were noted in either of the groups. Conclusions: Intralesional TA injection is as effective as I&C in cases of primary chalazia. So, injection may be considered as an alternative first-line treatment in cases where no biopsy is required.

Treatment of chalazia by incision and curettage versus intralesional triamcinolone acetonide injection