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Background and Aims: Enterococci are second most commonly isolated hospital-acquired pathogenfrom urinary tract and wounds. Being notorious organism enterococci has presented treatment challengesresulted in newer drug development followed by resistance development in segments; such as Vancomycin.Present study aims at detecting prevalence, distribution and susceptibility patterns of Vancomycin ResistantEnterococci (VRE) found in clinical isolates.Materials and Methods: A descriptive study was carried out in the Microbiology department of Tertiarycare hospital,Western India including a total of 36,027 clinical isolates received in the duration over 2 yearsfrom indoor patients across disciplines. Enterococci were recognized by standard biochemical tests. Antimicrobialsusceptibility testing was done as per CLSI guideline. VRE was distinguished by disc diffusionmethod and Minimum Inhibitory Concentration Test. Qualitative data were presented as proportions.Results: On susceptibility testing, the prevalence of VRE was found out to be 11.13%. Maximum numberof VRE isolates were from Urine (49.06%), followed by blood culture (32.08%), and swab (5.66%). AmongVRE; 56.6% isolates were E. Faecium followed by other enterococcus (35.85%) and E. Faecalis (7.55%)respectively. Highest resistance was found for penicillin, ampicillin and levofloxacin, while most sensitivewere linezolid and fosfomycin.Conclusion: Considering versatile ability to advance and transmit antimicrobial resistance, VRErepresents a bottle neck in treatment strategies. Rational prescription of antibiotic, VRE surveillance andtimely antibiogram in admitted cases is the need of hour.Keywords: Prevalence, Vancomycin resistant enterococci, Western India.

A descriptive study of vancomycin resistant enterococci in Tertiary Care Hospital of Western India