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This study was conducted on 100 children with β-thalassemia major aged between 1-15 years being regularly transfused at Department of Pediatrics, M.G.M. Medical College, after taking the consent from the parents and explaining them the purpose and method of study.   Mean serum values of ferritin, SGOT, SGPT was found to be 6416.9 ± 1581.8 μg/l, 205.4 ± 46.3 u/l and 254.6 ± 71.7 u/l in patients who received more than 100 transfusions while it was 3784.2 ±1304 μg/l, 104.9 ± 52.9 u/l, and 131.5 ± 63.6 u/l respectively for those who receive more than 100 transfusions   Youngsters with &amp;#62;100 transfusions had serum values of liver enzymes and iron overload higher when contrasted with those with &amp;#60;100 transfusions. The distinction in values between the two gatherings was seen as exceptionally huge (p esteem &amp;#60;0.001) Mean serum estimations of ferritin, SGOT, SGPT was seen as 6416.9 ± 1581.8 μg/l, 205.4 ± 46.3 u/l and 254.6 ± 71.7 u/l in patients who got in excess of 100 transfusions while it was 3784.2 ±1304 μg/l, 104.9 ± 52.9 u/l, and 131.5 ± 63.6 u/l individually for the individuals who get less than 100 transfusions.

To study the level of serum liver enzymes (SGOT & SGPT) in multitransfused thalassemia major patients