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Background: Acute respiratory distress syndrome (ARDS) is common outcome in patients with critical underlying diseases. The mortality rates of ARDS/ALI are generally reported to exceed 50% and range from 10 to 90%. Tropical disease like leptospirosis, dengue and malaria play role in the etiopathogenesis of ALI/ARDS. Methodology: It was an observational prospective study to detect the role of tropical diseases in etiopathogenesis of ARDS/ALI. Patients with diagnosis of ARDS/ALI having age more than 12 years and given written and informed consent were recruited in the study. Results: 37 cases of ARDS/ALI were enrolled in this observational prospective study. 3/4th patients were suffering from ALI and 1/4th patients were suffering from ARDS. Dyspnea and fever were common finding in these patients. Almost all patients had dyspnea and half of the patients had fever and almost 30% of the patients had hemoptysis. Conclusions: Leptospirosis play significant etiological role lead to ARDS/ALI and malaria is another tropical disease responsible for the same.  Keywords: ARDS; ALI; Leptospirosis; Malaria.

An observational prospective study to detect the role of leptospirosis and malaria in etiopathogenesis of ARDS/ALI