English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This study was undertaken to compare the efficacy of topical Bromfenac 0.09% and Prednisolone 1%. Materials and Methods: This was a prospective, double blind, comparative, interventional randomized controlled trial. Total of 180 patients were included in the study. Patients were randomized into two groups. Group A received Bromfenac 0.09% BD and Group B received Prednisolone 1% QID in tapering doses along with topical antibiotics post operatively. Both the groups did not receive any topical NSAIDs preoperatively. Patients preoperative grade of cataract by LOCS III Classification, post operative anterior chamber cells by SUN classification, Intraocular pressure were recorded and compared on day 3, 15 and 45 days. Results: A total of 180 eyes were included in the study of which 20 were lost to follow up 3 in Group A and 17 in Group B. Hence a total of 160 eyes 87 in Group A and 73 in group B completed follow up. The amount of inflammation did not differ significantly between Group A and Group B on day 3 (p=0.698) or on day 7 (p=0.325). At the end of 45 days none of the patients either in Group A or Group B had anterior chamber inflammation. IOP-There was no significant difference in IOP between the groups preoperatively (P= 0.18). But on the first follow up and subsequent follow ups there was significant difference in IOP between Group A and B (p<0.05) and this difference was increasing in trend as time passes (p value =0.00). Conclusion: Bromfenac can be used as an alternative to steroid drops in controlling post operative anterior chanber inflammation in all grades of cataract especially in steroid responders. Introduction Cataract surgery is the most frequently performed ophthalmic surgery. Postoperative inflammation is a common finding, due to the release of prostaglandins. The recent improvements in surgical technique have reduced the severity inflammation. Topical steroids are used after surgery for several weeks to reduce the postoperative inflammation. Steroids have a very good anti-inflammatory and analgesic effect but they also have risk of interference with wound healing, they may also cause intra ocular pressure rise and increase the risk of infection by compromising local immunity. As an alternative treatment Non Steroidal Anti Inflammatory Drugs (NSAID) can be used. NSAID’s are comparatively safer and they have multiple advantage like preventing intraoperative miosis if started preoperatively and prevention of cystoids macular edema post operatively. Bromfenac ophthalmic suspension 0.09% twice daily is one such newer drug now being used because of better potency and penetrability this has been approved in different countries for treatment of post cataract surgery inflammation and uveitis. In this study we report the results of a prospective randomized double masked trail comparing the efficacy of Bromfenac 0.09% and Prednisolone 1% for reducing the post operative inflammatory response. Materials and Methods The study obtained approval from the Institute Ethics Committee, and followed the principles of the Declaration of Helsinki. It is a prospective randomized clinical trial. This study was done between November 2015 to October 2016 at SDM College of Medical sciences and Hospital, Dharwad. All the patients who met inclusion criteria and exclusion criteria were included in the study. Inclusion Criteria 1. All patients with cataract aged more than 40 years undergoing phacoemulsification with posterior chamber intraocular lens implantation. Article Info Received: 15th March, 2019 Accepted: 13th May, 2019 Published Online: 9th September, 2019

To compare the effect of Bromfenac 0.09% and Prednisolone 1% on postoperative inflammation and intraocular pressure in phacoemulsification