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Background: Chronic renal failure (CRF) associated with many cutaneous manifestations starts fromxerosis, dark pigmentation, to life threatening severe uncontrolled itching. Cutaneous problems with CRFhaving different and newer manifestations after hemodialysis interventions.Aim: To assess the prevalence of cutaneous manifestations including hair and nails in chronic renal failure(CRF) patients on hemodialysis .Materials and Methods: One hundred patients of CRF undertaking hemodialysis were examined forvarious cutaneous presentations.Results: cutaneous manifestations seen in eighty six patients. The commonest finding was xerosis(81%),had wide range of clinical presentation with pruritus (56%) produced distress symptoms skincolor changes presented commonly as pallor (65%), and cutaneous hyperpigmentation (53%) manifestingphysical and psycological disturbance s respectively. Othera skin problem found peculiar to chronic renalfailure are acquired perforating dermatoses of kyrles diease (20%); prevalence of cutaneous infectionsespecially dermatophytosis and other superficial fungal infections (28%), pyoderma(10%) and viral (13%)infections; other important cutaneous manifestation are purpura (10%); and eczema(2%). The nail changessharing significant presentations in majority of renal failure patients which included half and half nail(20%),as important clinical marker followed by koilonychia (16%), onychomycosis (16%), onycholysis(11%), Mees’ lines (7) Hair changes also contributing significant clinical finding as sparse body hair (27.Wide array of oral mucosal changes presented mainly as macroglossia (36%), xerostomia (28%), ulcerativestomatitis (27%), and uremic odour(7%).Conclusions: CRF had a significant cutaneous changes mainly as xerosis, pruritus acquired perforatingdermatoses, uraemic odour and hyperpigmentation. These changes served as clinical clue in diagnosisand therapeutic management. These changes were attributed by disease (CRF) as we

Cutaneous manifestations in patients with chronic renal failure on hemodialysis