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Urticaria more commonly known as “ Nettle rash ” or hives, presents as circumscribed,raised (oedematous), usually pruritic evanescent skin lesions. The lesions may be pink or red, althoughclassifiably they are pale wheals surrounded by an erythematous flare. Approximately 15% to 20% of thegeneral population will have urticaria at least once during their lifetime. Persons of any age may experienceurticaria and/or angioedema.Materials and Methods: 150 cases of chronic urticaria of both sexes and of different age group wereselected from the out patient department of Dermatology, Narayan medical college Sasaram Bihar. Caseshaving more than 6 weeks of duration of disease were included in the study.Result: The maximum no of cases were seen in the age group of 25-34 years (34.6%), in 35-44 years nocases are 25.4%, 21.4% in age group 15-24 yrs and 18.6% in age group 45-55. duration of chronic urticariaranging from 6 weeks to 24 months. Maximum numbers of cases (66.67%) were having duration up to 12months. Only 33.33% were having duration more than 12 monthsDiscussion and Conclusion: Maximum number of patients presented with the duration of disease of 12months.Finding suggest association of cyst of Amoeba and Giardia in some cases. Raised serum TSH and IgE levelwas seen in some cases. Non veg diet especially fish was associated with Chronic Urticaria.Antihistamines are the most effective and preferred drug for the treatment of Chronic Urticaria.Traditionalantihistaminic (hydroxyzine) and second generation antihistamines (levocetrizine and fexofenadine) wasprescribed in therapeutic dosages and there results were interpreted.Keywords: Urticaria, Management, Aetiopathogenesis.

Aetiopahogenesis and management of chronic urticaria -A Study