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Introduction: Purpose of our research study was to sort out differences in levels of Na+ and K+ in blood sample from venous and arterial system, collected simultaneously in severely diseased patients. Materials and Methods: In our cross section compar ative research study, total 100 p atients admitted in intensive care unit were analyzed for measurement of sodium and potassium levels from arterial and venous blood samples collected from femoral ar tery by heparinised syringe and from median cubital vein b y red vacutainer correspondingly at the similar time. ABG Analyzer machine was used for measurement of electrolytes from arterial blood, while ISE Electrolyte analyzer machine w as used for measurement of electrolytes from venous blood. Result: Potassium of venous blood sample (4.49 ± 0.63 mmol /l) was significantly higher as compared to arterial blood sample (4.02± 0.59 mmol /l). The mean sodium of venous blood sample (139.86 mmol/L) was significantly higher than arterial blood sample (136.32 mmol/L). The mean Bias for potassium and sodium 0.15 mmol/l and 1.54 mmol/ l correspondingly. Conclusion: Arterial Blood Gas analyzer is not comparable to Electrolyte analyzer machine for measurement of Na+ and K+ levels. Arterial Blood sample analyzed by Arterial Blood Gas analyzer cannot substitute venous blood sample analyzed by electrolyte analyzer for electrolytes analysis, even if TAT (Turn Around Time) of Arterial Blood Gas analyzer is low. © 2019 Published by Innovative Publication.

international journal of clinical biochemistry and research

Comparative study of electrolyte (sodium and potassium) measurement in severely diseased patient by venous &amp; arterial blood collected at the similar time