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Endotracheal tube is an airway catheter inserted in the trachea to assure patency of the upperairway. ETT cuff seals the trachea to facilitating positive-pressure ventilation and to prevent aspiration.The cuff pressure of an endotracheal tube depends on various patient-related factors like obesity, old age,environmental circumstances and therapeutic interventions. Physiological changes in laparoscopic surgeryunder general anesthesia, due to pneumoperitoneum and change in patient position can affect ETT cuffpressure. These changes in ETT cuff pressure can lead to significant peri-operative adverse outcome.Aims and Objectives: To evaluate the changes in ETT cuff pressure between open and laparoscopiccholecystectomy under general anesthesia.Materials and Methods: 80 ASA grade I/II patients, aged 20-50 years, undergoing laparoscopic or opencholecystectomy, under GA were included in this prospective observational study. Patients were dividedin two equal sized groups (N=40) for laparoscopic and open cholecystectomy. ETT cuff pressures wererecorded with ETT manometer, at 5 min intervals until extubation. Patients were followed 6 hourly, for 24hours to record any postoperative complications.Result: The changes in hemodynamic parameters were more in laparoscopic surgery than open surgery.Abdominal insufflation in laparoscopic surgery causes significant increase in cuff pressure due to alteredthoracic compliance. Change in position, during laparoscopic surgery, also affects endotracheal tube cuffpressure.Conclusion: The pneumo-peritoneum and positional changes during laparoscopic surgery causesignificant increase in endotracheal tube cuff pressure and thus associated with an increased incidenceof post-operative complications.Keywords: General anaesthesia, Endotracheal tube cuff, Tube cuff pressure, Laparoscopic, Cholecystectomy.

Changes in endotracheal tube cuff pressure during the open and laparoscopic surgery