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Background: Spinal anesthesia is a preferable technique for lower abdominal surgeries as it provideseffective sensory and motor block with rapid onset, attenuation of stress response and less thromboembolicepisodes. It is currently known that levobupivacaine and racemic bupivacaine have similar analgesicpotencies for epidural and spinal anesthesia. Due to the adverse cardiac effects of racemic bupivacaine,several studies have been performed in order to find anesthetic compounds to take its place.Aim: To compare and evaluate the efficacy between 0.5% isobaric Levobupivacaine and 0.5% racemicBupivacaine in spinal anesthesia among the patients undergoing lower abdominal and lower limb surgeries.Materials and Methods: A prospective comparative study was conducted for a period of one year at ourhospital under the department of anesthesia. Based on purposive sampling 200 subjects were selected forthe study and were divided into two groups. The study subjects were randomly allocated into two groupsof 100 each. Group B subjects received 3ml of 0.5% intrathecal hyerbaric Bupivacaine (15 mg) and groupL patients received .5% intrathecal Isobaric Levobupivacaine (15 mg). The mode of onset and the durationof motor and sensory block were assessed and the subjects were monitored for blood pressure, peripheraloxygen saturation (SpO2), and pulse rate at 1st, 3rd, and 5th min and every 5 min up to the 30th min, andthen every 10 min until the end of the operation.Results: The onset and the duration of motor and sensory block did not show statistical significantdifference between the bupivacaine and levobupivacaine. The incidence of hypotension and bradycardiawas more among the bupivacaine group than that of the levobupivacaine group and the difference was foundto be statistically significant (p

indian journal of clinical anaesthesia

A comparative study of the anesthetic potencies and hemodynamic changes of 0.5% isobaric levobupivacaine and 0.5% hyperbaric racemic bupivacaine for spinal anesthesia in lower abdominal and lower limb surgeries