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Background: Central neuraxial blockade is the most widely used form of regional anesthesia in surgeriesinvolving abdominal, urological, obstetric, gynaecological and lower limb. The nerve blocking propertiesof the R and S-enantiomers were similar but that the S-enantiomer was less cardiotoxic. The aim ofour study is to compare the efficacy and haemodynamic response between intrathecal hyperbaric 0.5%Bupivacaine with isobaric 0.75% Ropivacaine using Fentanyl as adjuvant in patients undergoing infraumbilical surgeries.Materials and Methods: 60 patients of age group between 25 – 65 years belonging to American Society ofAnaesthesiologist (ASA) 1 and 2 posted for general surgical, urological, orthopaedic and gynaecologicalprocedures involving lower abdominal surgeries under spinal anaesthesia divided into two groups of 30each and randomly allocated to one of the two below mentioned groups:Bupivacaine group (Group B) n=30; Ropivacaine group (Group R) n=30Observation and Results: Chi-square test and Student’s ‘t’ test were used to analyse the results. Thesensory block in Bupivacaine group B was significantly higher compared to Ropivacaine group R attainingstatistical significance. The 3 minutes motor block, incidence of hypotension was denser and higher inBupivacaine group compared with Ropivacaine group. Incidence of bradycardia was not significantlydifferent between the two groups. Although the onset of motor blockade was denser in Bupivacaine group,the total duration of motor blockade was similar between the groups.Conclusion: We conclude from our study that 0.75% isobaric Ropivacaine produces similar duration ofefficacy with stable haemodynamics, as compared with 0.5% hyperbaric Bupivacaine.Keywords: Bupivacaine, Ropivacaine, Fentanyl, Motor blockade, Infra umbilical surgeries.

indian journal of clinical anaesthesia

Comparing the efficacy and haemodynamic response between intrathecal hyperbaric 0.5% bupivacaine with isobaric 0.75% ropivacaine using fentanyl as adjuvant in patients undergoing infra umbilical surgeries