English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Background and Aims: Etomidate is used for induction of anaesthesia in haemodynamically unstablepatients but its use is associated with undesirable side effects like myoclonus, incidence of which is 50-80%. This prospective, randomized, placebo controlled study is to compare the effect of dexamethasoneand fentanyl for prevention of etomidate induced myoclonus.Materials and Methods: Ninety adult patients were randomly assigned into three groups to receiveDexamethasone (group D), Fentanyl (group F) and placebo (group P) five min before injection etomidate0.3mg/kg IV. The patients were assessed for myoclonus using a four point intensity scoring system over aperiod of 5 min. ANOVA and chi square test were used for statistical analysis and Pas statistically significant.Results: The incidence of myoclonus was significantly reduced in groups D and F compared with group P(p value 0.001).The incidence of pain associated with Etomidate induced myoclonus also was significantlyreduced in groups D and F compared to group P (p value 0.001).Conclusion: Dexamethasone significantly reduces the incidence of myoclonus as compared to placebo. Italso significantly reduces the pain associated with Etomidate injection. However its efficacy to reduce painand myoclonus as compared to Fentanyl is much less.Keywords: Etomidate, Myoclonus, Dexamethasone.

indian journal of clinical anaesthesia

A comparison of fentanyl and dexamethasone pretreatment for prevention of etomidate induced myoclonus, a randomized double blind placebo controlled study