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In the practice of paediatric anaesthesia, intubation of trachea without using neuromuscularblocking agents is becoming commoner more so in conditions in which muscle relaxants are not preferred.Different combinations of drugs including opioids, intravenous agents and inhalational agents are beingused for facilitating endotracheal intubation when muscle relaxants are not used. In this study we comparedintubating conditions in paediatric patients after sevoflurane induction and propofol in two different doses.Materials and Methods: 80 children of 2 to 12 years age undergoing elective surgeries were divided intotwo groups P2 and P3 of 40 each. After sevoflurane induction and fentanyl 2mcg/kg I.V. group P2 receivedpropofol 2mg/kg and group P3 received propofol 3mg/kg I.V. The two groups were compared with respectto intubating conditions and haemodynamic parameters.Results: Clinically acceptable intubating conditions were seen in all patients in both groups. Excellentintubating conditions were more in group P3 (87.5%) than group P2 (80%). Haemodynamic parametersshowed no significant difference between the two groups.Conclusion: In paediatric patients, endotracheal intubation can be comfortably performed without musclerelaxants by using propofol and fentanyl with sevoflurane induction with no respiratory or haemodynamicadverse events. Propofol in a dose of 3mg/kg gives better intubating conditions than 2mg/kg withoutadverse haemodynamic effects, although 2mg/kg propofol also gives acceptable intubating conditions.Keywords: Paediatric patients, Intubating conditions, Propofol, Sevoflurane.

indian journal of clinical anaesthesia

Comparing two different doses of propofol after sevoflurane induction for intubation in paediatric patients without use of neuromuscular blocking agents