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Postoperative pain is the most annoying symptom that every patient will complain after thesurgery. Relief of this pain greatly improves the patient satisfaction, compliance and recovery. Opioids andNSAIDs are the most commonly used analgesics in the postoperative period. The need for the study was tocompare the efficacy of intravenous Nalbuphine over intravenous Paracetamol in the postoperative period.Materials and Methods: 60 patients who underwent elective surgeries under general anaesthesia wereselected for the study. 30 patients in Group P received Inj. Paracetamol 15 mg/kg body wt. and 30 patientsin Group N received Inj. Nalbuphine-0.15 mg/kg body wt over 15 min. Both the groups received the studydrug half an hour before the completion of surgery.Postoperative pain scores were measured using VAS pain score and postoperative haemodynamicparameters were measured at regular intervals. The time for the first dose of rescue analgesia was noted.Side effects like sedation, nausea, vomiting, pruritus were assessed at regular intervals postoperatively until10 hours.Results: Demographic profile were comparable between the groups. Both Nalbuphine and Paracetamolcan be effectively used for treating postoperative pain. But Nalbuphine is used as safer alternative sincethe duration of analgesia is longer in Nalbuphine group when compared to Paracetamol group withoutsignificant side effects. Haemodynamic stability was maintained in both the groups.Conclusions: IV Nalbuphine is a better cost effective alternative to IV Paracetamol in alleviating thepostoperative pain with prolonged duration of analgesia and hemodynamic stability without significantside effects.Keywords: Intravenous Nalbhupine, Paracetamol postoperative analgesia, VAS score, Haemodynamic variables sedation.

indian journal of clinical anaesthesia

Comparasion of intravenous Nalbuphine versus intravenous Paracetamol for postoperative analgesia in patients undergoing surgeries under general anaesthesia