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Aim: Blood transfusion is a life-saving therapeutic intervention and essential element of a health care system that plays a crucial role in the overall management of patients. Transfusion-transmissible infectious agents such as Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV) and Syphilis are among the greatest threats to blood safety for recipients and WHO has recommended that these diseases should be screened to get safe blood. This study aimed to evaluate the prevalence of transfusion transmissible infections (TTI) among donors at District Hospital of Palanpur and compare it with other studies. Material and Methods: HBV, HCV and HIV were tested by ELISA and RAPID methods approved by NACO in voluntary as well as replacement blood donors. RPR was carried out for screening of syphilis. Results: Seroprevalence of Transfusion Transmitted Infections (TTIs) among blood donor is 1.712%. The prevalence of HIV, HBV, HCV and syphilis was found to be 0.043%, 0.259% 0.173% and 0.302% respectively in voluntary blood donors as against 0.238%, 1.549%, 0.715% and 1.788% being the seroprevalence of HIV, HBV, HCV and syphilis in replacement blood donors. The seroprevalence of TTIs in replacement donors (4.290%) is higher than voluntary donors (0.777%). Conclusion: Voluntary blood donors have been found to be safer than replacement blood donors. The present study concluded that motivating voluntary blood donors and diligent donor selection are the most effective way of ensuring adequate supplies of safe blood on a continuing basis.

Seroprevalence of transfusion transmitted infections among blood donors at district hospital of banaskantha in North Gujarat, India