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Endodontic treatment success depends on biomechanical preparation and 3-D obturation. Mandibular premolars have been reported with aberrant anatomy. The endodontic treatment of mandibular premolars may have major failure due to unrecognized or untreated multiple canals when they are present. Hence a thorough knowledge of the root canal morphology, careful radiographic interpretation and access cavity modifications are essentials for enhancing endodontic procedures.Keywords: Mandibular premolars, multiple canals, root canal treatment.

Endodontic Enigma: A case report series of mandibular premolars with two root canals