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Jácome C1,2, Pereira AM2,3, Almeida R1,2, Amaral R1,4, Correia MA3, Mendes S1, Vieira-Marques P1, Ferreira JA5, Lopes I5, Gomes J5, Vidal C6, López Freire S6, Méndez Brea P6, Arrobas A7, Valério M7, Chaves Loureiro C7, Santos LM7, Couto M3, Araujo L3, Todo Bom A8, Azevedo JP9, Cardoso J10, Emiliano M10, Gerardo R10, Lozoya C11, Pinto PL12, Castro Neves A12, Pinto N12, Palhinha A12, Teixeira F13, Ferreira-Magalhães M13, Alves C14, Coelho D14, Santos N15, Menezes F16, Gomes R16, Cidrais Rodrigues JC17, Oliveira G17, Carvalho J17, Rodrigues Alves R18, Moreira AS18, Costa A19, Abreu C20, Silva R20, Morête A21, Falcão H22, Marques ML22, Câmara R23, Cálix MJ24, Bordalo D25, Silva D26, Vasconcelos MJ26, Fernandes RM27,28, Ferreira R27,29, Freitas P30, Lopes F31, Almeida Fonseca J1,2,3,31, INSPIRERS group 1Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal 2Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Porto, Portugal 3Allergy Unit, Instituto and Hospital CUF, Porto, Portugal 4Dept. of Cardiovascular and Respiratory Sciences, Porto Health School, Polytechnic Institute of Porto, Porto, Portugal 5Serviço de Imunoalergologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal 6Servicio de Alergia, Complejo Hospitalario Universitario de Santiago, Santiago De Compostela, Spain 7Serviço de Pneumologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal 8Serviço de Imunoalergologia, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal 9Imunoalergologia, Centro Hospitalar de Leiria, Leiria, Portugal 10Serviço de Pneumologia, Hospital Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal 11Serviço de Imunoalergologia, Hospital Amato Lusitano, Unidade Local de Saúde de Castelo Branco, Castelo Branco, Portugal 12Serviço de Imunoalergologia, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal 13Serviço de Pediatria, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto, Portugal 14Serviço de Pneumologia, Hospital Nossa Senhora do Rosário, Centro Hospitalar Barreiro Montijo, Barreiro, Portugal 15Serviço de Imunoalergologia, Centro Hospitalar Universitário do Algarve, Portimão, Portugal 16Serviço de Pneumologia, Hospital Garcia de Orta, Almada, Portugal 17Serviço de Pediatria, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, Matosinhos, Portugal 18Serviço de Imunoalergologia, Hospital do Divino Espirito Santo, Ponta Delgada, Portugal 19Serviço de Pediatria, Hospital da Senhora da Oliveira, Guimarães, Portugal 20Serviço de Imunoalergologia, Hospital São Pedro de Vila Real, Centro Hospitalar De Trás-Os-Montes E Alto Douro, Vila Real, Portugal 21Serviço de Imunoalergologia, Hospital Infante D. Pedro, Centro Hospitalar Baixo Vouga, Aveiro, Portugal 22Serviço de Imunoalergologia, Centro Hospitalar Universitário do Porto, Porto, Portugal in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol. 2013;132(5):1086-96. 8. Ramakrishnan S, Camp JR, Vijayakumar B, Harding FM, Downs ML, Russell REK, et al. The Use of Benralizumab in the Treatment of Near Fatal Asthma: A New Approach [published online ahead of print, 2020 Feb 5]. Am J Respir Crit Care Med. 2020;10.1164/rccm.202001-0093LE. 9. Tello K, Hoffmann A, Beutel B, Greulich T, Vogelmeier CF, Richter MJ, et al. Anti-interleukin-5 therapy (mepolizumab) in life-threatening asthma attack: A case-based discussion. Respir Med Case Rep. 2019;28:100927. 10. Ryman JT, Meibohm B. Pharmacokinetics of monoclonal antibodies. CPT Pharmacometrics Syst Pharmacol. 2017;6(9):576-88.

Validation of App and Phone Versions of the Control of Allergic Rhinitis and Asthma Test (CARAT)