English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Synaptic pruning is a physiological mechanism of neuroplasticity, which is regulated through synthesis  of growth polypeptides, neurotrophins. The role of neurotrophins in the mechanism of synaptic pruning in patients  with hereditary pathology of peripheral motor neuron was studied in a clinical experimental trial. It was found that  patients had elevated levels of regulatory growth polypeptides, which led to the axon growth inhibition effect  in organotypic tissue cultures. Thus, neurotrophin overexpression can be considered as a factor preventing synaptic  pruning and contributing to further process of neurological degeneration in nerve tissue in patients with hereditary  pathology of peripheral motor neuron.

The role of polypeptide compounds in mechanism of CNS plasticity in patients with hereditary pathology of peripheral motor neuron