English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), glutathione  reductase (GR), glutathione transferase (GST), the content of reduced glutathione (GSH) and malondialdehyde (MDA)  were investigated in the samples of the tumor, peritumoral zone and healthy tissue, taken at the line of resection,  were obtained from 14 patients with primary squamous cell carcinoma of the vulva, and 13 patients with  local recurrence appeared in the period from 3 months to 7 years. by conventional spectrophotometric methods.  The content of GSH and the activity of SOD, GPx, GR, GST were significantly increased, while MDA was decreased  in the tissue of the primary carcinoma of the vulva in compared with the healthy tissue. Differences in the functioning  of the investigated system of enzymes in the peritumoral zone were also revealed in the primary and recurrent tumoral  process. Similar but much less pronounced changes were also observed in the recurrent tumor. It is suggested that such  dynamics of activity of the studied system with the progression of cancer process can be the result of adaptation  to changes in the local biochemical status of healthy (nonmalignant) tissue of the organ carrying the tumor and reflect  the metabolic features of the recurrent tumor.

The activity of redox-regulatory systems in the primary and recurrence tumors in vulvar cancer