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A series of substituted ( E )-2-benzylidenehydrazinecarbothioamide compounds were synthesized by condensation of thiosemicarbazide with substituted benzaldehydes. The synthesized substituted ( E )-2-benzylidenehydrazinecarbothioamide compounds were characterized by their physical constants, UV, IR and NMR spectra. The antimicrobial activities of these synthesized substituted ( E )-2-benzylidenehydrazinecarbothioamide compounds have been screened by Bauer-Kirby method using human pathogenic bacteria and fungal species. The antimicrobial activities of all synthesized ( E )-2-benzylidenehydrazinecarbothioamide compounds have shown significant activity.

international letters of chemistry, physics and astronomy

Synthesis, Characterization and Evaluation of Biological Activity of some Substituted(&lt;i&gt;E&lt;/i&gt;)&lt;i&gt;-&lt;/i&gt;2-Benzylidenehydrazinecarbothio Amides