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The purpose of the present pilot study was to evaluate the incidence of photoallergic reactions to selected non-steroidal anti-inflammatory agents, chemicals used in dental composites and antiseptic agents (Triclosan) among dental professionals (dentists, nurses and attendants) and dental patients. A total of 59 participants were included: 25 occupationally exposed dental Original Article MedInform I S S U E 2 , 2 0 1 5 166 MedInform professionals and 34 dental patients. Skin photopatch testing with Methylhydroquinone, Camphorquinone, Benzydamine hydrochloride, Triclosan, and Ibuprofen (Chemotechnique Diagnostics) was performed, according to: Photopatch testing: a consensus methodology for Europe. No reactions of photosensitization to Methylhydroquinone and Camphorquinone were observed. Highest rates of contact sensitization to Triclosan, especially among men and dental patients were established, but no reactions of photosensitization. Our results indicate risk of sensitization to Triclosan in consumers, but not in occupational exposure. We could consider Ibuprofen as second of importance allergen for all the groups defined by us, but no photosensitizing action was found. The only positive skin patch test reactions after UV-irradiation observed in the present study were to Benzydamine hydrochloride, in the groups of women (0.0% vs 6.9%) and in the one of dental professionals (0.0% vs 4.0%). According to our results, Benzydamine hydrochloride is the only of the substances exerting photosensitizing action, and dental professionals and women could be outlined as groups at risk. However, further work is needed to validate the reliability of these findings.

medinform

Pilot Study Of Photoallergic Reactions To Non-steroidal Anti-inflammatory Agents, Chemicals Used In Dental Composites And Antiseptic Agents Among Dental Professionals