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The aim of this study was to evaluate the effects of citrulline malate (CIT) supplementation on aerobic and muscular endurance in young adult males. Eighteen young adult men (age: 21.5 ± 2.7 years) were randomized into two groups (Citrulline malate - CIT and Placebo - PLA; N = 9/group ) and received the respective supplements for 7 days. The CIT group was supplemented with 6 g CIT + 6 g dextrose (total: 12 g), while the PLA group received the same amount (12 g) of dextrose. At the pre- and post-supplementation, the following variables were analyzed: aerobic (maximal treadmill test, Tmax) and muscle (repetitions maximum test, Rmax) endurance tests, as well as mean and maximum heart rate (HR) in Tmax and ratings of perceived exertion (PSE) in Rmax. No significant (P > 0.05) differences were found between CIT and PLA groups in time until exhaustion in Tmax, total repetitions in Rmax, maximal HR and PSE from pre- to post-supplementation. The mean HR was statistically lower (P < 0.05) in the CIT group compared to the PLA in the Tmax. In conclusion, supplementation of CIT (6 g / day) does not improve aerobic and muscular endurance, as well as maximal HR or PSE in healthy young adults, despite reducing the mean HR during the maximal incremental test. Keywords: Endurance Training. Dietary Supplements. Physical Functional Performance. Citrulline. Nitric Oxide. ResumoO objetivo deste estudo foi avaliar os efeitos da suplementacao de citrulina malato (CIT) sobre a resistencia aerobica e muscular em homens adultos jovens. Em um desenho experimental randomizado, duplo-cego e controlado com placebo, dezoito homens adultos jovens (idade: 21,5 ± 2,7 anos) foram randomizados em dois grupos (Citrulina malato – CIT e Placebo – PLA; N = 9/grupo) e receberam os respectivos suplementos por um periodo de 7 dias. O grupo CIT foi suplementado com 6 g de CIT + 6 g de dextrose (total: 12 g), enquanto o grupo PLA recebeu a mesma quantidade (12 g) de dextrose. Nos momentos pre e pos suplementacao as seguintes variaveis foram analisadas: resistencia aerobia (teste incremental maximo em esteira rolante, Tmax) e muscular (teste de repeticoes maximas, Rmax), bem como a frequencia cardiaca (FC) media e maxima no Tmax e a analise da percepcao subjetiva de esforco (PSE) no Rmax. Nenhuma diferenca significante (P > 0,05) foi encontrada entre os grupos CIT e PLA no tempo ate a exaustao no Tmax, total de repeticoes no Rmax, FC maxima e PSE do momento pre para o pos suplementacao. A FC media foi estatisticamente (P < 0,05) menor no grupo CIT comparado ao PLA no Tmax. Em conclusao, a suplementacao de CIT (6 g/dia) nao melhora a resistencia aerobica e muscular, bem como a FC maxima ou PSE em adultos jovens saudaveis, apesar de reduzir a FC media durante o teste incremental maximo. Palavras-chave: Treino Aerobico. Suplementos Nutricionais. Desempenho Fisico Funcional. Citrulina. Oxido Nitrico.

Effects of Citrulline Malate Supplementation on Aerobic and Muscular Endurance in Young Adults Men