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A dengue se tornou um problema crescente de saude publica devido as altas taxas de mortalidade e morbidade, alem de impor uma carga economica substancial em um pais em desenvolvimento. O presente estudo objetivou revisar de forma sistematica a literatura cientifica atual para sintetizar o efeito do impacto economico do tratamento de pacientes com dengue no Brasil. A pesquisa foi realizada entre os meses de agosto a outubro de 2019, nos bancos de dados Medical Literature Analysis and Retrieved System (MEDLINE), Literatura Latino-americana e do Caribe em Ciencias da Saude (Lilacs) e Biblioteca Digital Brasileira de Teses e Dissertacoes (BDTD), totalizando uma amostra final de oito estudos. Diante dos achados, ficou evidente a escassez de estudos que abordam a tematica do impacto na economia brasileira em consequencia do tratamento de pacientes com dengue, revelando, a necessidade de investimentos em pesquisas cientificas continuadamente, principalmente nas localizacoes geograficas distantes dos grandes centros de pesquisas cientificas localizados na regiao Sudeste do pais. O impacto do tratamento da doenca no pais e substancial, e, portanto, espera-se que este estudo possa estimular a expansao cientifica no pais e orientar os formuladores de politicas para novas intervencoes na saude publica, a fim de diminuir a propagacao da doenca e minimizar dispendios aos cofres publicos.   Palavras-chave: Custos e Analise de Custo. Assistencia a Saude. Dengue. Gastos em Saude. Gestao em Saude.     Abstract Dengue has become a growing public health problem due to its high mortality and morbidity rates, as well as imposing substantial economic burden stemming from a developing country. The present study aimed to systematically review the current scientific literature to synthesize the economic impact effect of dengue patients treatment in Brazil. The research was performed between August and October 2019, in the Medical Literature Analysis and Retrieved System (MEDLINE), Latin American and Caribbean Literature in Health Sciences (Lilacs) and Brazilian Digital Library of Theses and Dissertations (BDTD), totaling a final sample of eight studies. In view of the findings, it was evident the scarcity of studies addressing the theme of the impact on the Brazilian economy as a result of the dengue patients treatment, revealing the need for investments in scientific research continuously, especially in the geographical locations distant from the large scientific research centers located in the Southeast region of the country. The impact of the  disease treatment in the country is substantial, and therefore it is expected that this study can stimulate scientific expansion in the country and guide policymakers to new interventions in public health, in order to reduce the spread of the disease and minimize expenditures to public coffers.   Keywords: Costs and Cost Analysis. Health Care Delivery. Dengue. Health Expenditures. Health Management.

Impacto Econômico do Tratamento de Pacientes com Dengue no Brasil: uma Revisão Sistemática