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Backgr о und. Сomplex regional pain syndrome is a condition associated with a multitude of clinical factors. Its characteristic feature is persistent pain caused by injuries and is not anatomically limited to the location of a particular peripheral nerve. Clinical case. This article describes a case involving the treatment of complex regional pain syndrome in a thirteen-year-old patient, which resulted in a simple bone cyst surgical treatment of the lower-third of the fibula. Diagnostics were based on clinical, laboratorial, histological, radiological, and instrumental methods of research. The treatment methods included medication (nonsteroidal anti-inflammatory drugs, antidepressants, antipsychotics, anticonvulsants, non-opioid analgesics of central action, and bisphosphonates), cold plasma ablation, neurolysis of the sural nerve, prolonged regional anesthesia, tunneling of the bone marrow cavity (filled by substitutional filler), and marginal bone resection. Discussion. Сomplex regional pain syndrome is a poorly studied condition, which contributes to the complexity of its diagnosis. In this case, the presence of complex regional pain syndrome can be characterized by tissue injury during surgical intervention as well as by intraoperative injury of the nerve fibers. The stages of complex regional pain syndrome detected in studies may not appear in all patients, and in this case, no staging was observed. By eliminating the obliteration of the medullary canal after segmental resection of the sclerosed portion of the bone, it was possible to reduce the severity of pain, which resulted in the subsequent disappearance of the manifestations of complex regional pain syndrome. Conclusions. This case testifies to the effectiveness of various methods of treating complex regional pain syndrome. The etiology of the specific patient’s pain syndrome should be considered when treating complex regional pain syndrome.

Treatment of complex regional pain syndrome after filling a single bone-cyst cavity with beta-tricalcium phosphate granules