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Objective. To study the microbial and biological properties of the dominant species of causative agents of infectious and inflammatory complications after cardiac surgery. Infectious and inflammatory complications (IIC) developing after cardiac surgery with sternal approach such as thoracic and rib osteomyelitis, sterno-mediastinitis are severe life threatening states. Materials and methods. Bacteriological study of the sternal wound discharge from 178 patients with different infectious and inflammatory complications after sternotomic open-heart surgeries was conducted. Biological properties of isolates were investigated. Results. There were detected 242 strains of microorganisms referring to different taxons. Gram-positive bacteria, in particular, S. aureus and S. epidermidis prevailed. Out of gram-negative bacteria, prevailed P. aeruginosa and E. coli . All isolates S. aureus and P. aeruginosa possessed different factors of virulence and persistence including ability to biofilm formation. Carbapenems displayed the greatest bactericidal activity in relation to S. aureus and P. aeruginosa . Conclusions. The obtained data permit to optimize the preoperative preparation of cardiac surgery patients.

Species diversity and biological properties of dominant species of causative agents of poststernotomic infectious complications in cardiac surgery