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Background : Confocal microscopy is a modern examination method that enables real-time, noninvasive in vivo imaging of the cornea, limb, and conjunctiva. Aim : To evaluate the main morphological changes observed using confocal microscopy in patients with pseudoexfoliation (PEX) syndrome. Methods : Overall, 21 patients were examined: 12 with PEX syndrome were enrolled in the examination group and nine patients without PEX in the control group. Results : In patients with PEX, a decreased cell density in the epithelium and stroma of the cornea as well as a significant increase of hyper-reflective intercellular microdeposits and dendritic cells was observed (p < 0.05).

The influence of pseudoexfoliative syndrome on corneal morphology based on in vivo confocal microscopy