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Results: Overall, S. aureus showed resistance to 6 antibiotics including oxacillin (83.3%), ceftazidime (66.6%), penicillin (50%), trimethoprimsulfamethoxazol (41.6%), cefixime (33.3%) and vancomycin (8.3%). The highest minimum inhibitory concentrations (MIC) values of extract were found to be 250 ppm against 12 strains and the least value was 63 ppm against 2 strains. Conclusions: Ethanol extract of W. somnifera leaf might be exploited as natural drug for the treatment of several infectious diseases caused by this pathogen.

Evolution of Antimicrobial Activity of Leaf Extract of Withania somnifera Against Antibiotic Resistanct Staphylococcus aureus