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Rhythmic oscillatory patterns permeate the entire universe and sustain cellular dynamics at biological level. There is compelling evidence that our cells are sensitive to physical stimulation and can be exposed to physical energies to afford efficient rescue of damaged organs. A vivid example of such a novel view is provided by the unprecedented discoveries in the field of mechaobiology, and photobiomodulation. Seeing cell biology, and in particular stem cell biology, with the eyes of Physics may help developing a novel path in Regenerative/Precision Medicine. These issues are the main core of the 5th International Basic Research Meeting of the International Society for Medical Shock Wave Treatment (ISMST), scheduled in Bologna on June 28th-29th, 2018, entitled “Physical Tissue Stimulation, a path to self-healing” [1].

Regenerative Medicine on the Verge of the 4th Industrial Revolution: What We May Envision When the Physical, the Biological and the Digital Converge