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The aim of the investigation was to determine priority risk factors of developing cor pulmonale in patients with chronic obstructive pulmonary disease (COPD) using correlation analysis. Materials and Мethods. 71 patients with moderate and severe COPD treated in the in-patient department of City Clinical Hospital No.10 (Nizhny Novgorod) have been examined. To characterize a nutritional status, body mass index, waist measurements, waist/height ratio have been determined. Dyspnea and CPOD severity according to mMRC scale, CAT test; oxygen saturation; external respiration function values have been evaluated; Doppler echocardiographic examination has been carried out. Results. A severe COPD course with low values of spirographic parameters correlates with pathologic remodeling of the right parts of the heart and pulmonary hypertension. An essential risk factor of developing cor pulmonale is comorbid abdominal obesity. The role of the latter especially grows in the group with severe COPD. A thoroughly conducted correlation analysis was of great value in revealing "intimate" mechanisms of developing remodeling of the right parts of the heart in chronic obstructive pulmonary disease in comorbid conditions.

Priority Risk Factors of Developing Cor Pulmonale in Patients with Chronic Obstructive Pulmonary Disease According to Correlation Analysis Findings