Open AccessA Novel Plant Sesquiterpene Lactone Derivative, DETD-35, Suppresses BRAF V600E Mutant Melanoma Growth and Overcomes Acquired Vemurafenib Resistance in Mice
Author(s) -
Jia-Hua Feng,
Kyoko NakagawaGoto,
KuoHsiung Lee,
LieFen Shyur
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/sak8-jj53
Subject(s) - vemurafenib , melanoma , mutant , cancer research , sesquiterpene lactone , medicine , mutation , v600e , sesquiterpene , stereochemistry , chemistry , biochemistry , metastatic melanoma , gene