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The article explores the problems of strategic analysis of the spatial development of Siberian regions. It has been shown that the inclusion of mesoregional entities in the strategic spatial planning system allows improving the quality of strategic studies of the promising development of macroregions. The current state and problems of socio-economic development of the Sayano-Yenisei mesoregion located in the southern part of Eastern Siberia on the territory of three constituent entities of the Russian Federation (the Krasnoyarsk Krai, the Republic of Khakassia and the Republic of Tuva), in the Yenisei river basin, in the basin of the Eastern and Western Sayan mountains and Kuznetsk Alatau are analyzed. The article considers opportunities, limitations and prospects of advanced economic development of mesoregion. An intersectoral regional model was proposed for the study of promising development scenarios, which would link the parameters of investment development projects with macroeconomic regional indicators. A macroeconomic assessment of the impact of projects on indicators of social and economic development of territories has been performed

Strategic Analysis of the Prospects for the Sayano-Yenisei Mesoregion Using the Balance Model