English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: Hepatitis B vaccination is recommended for all health care workers as they constitute a high-risk group for acquiring blood borne hepatitis B infection. Anti HBs level ≥10 mIU/ml at any time after vaccination is considered as a marker of sustained immunity, which provides protection against infection. Poor sero-protection rates to hepatitis B vaccine are recognized and some individuals do not develop sufficient levels of anti-HBs antibodies. Hence, it is necessary to identify the individuals who are non-protective responders to vaccination. With this background, the present study was undertaken to determine immune response to hepatitis B vaccine amongst the health care workers. Material and Methods: The present cross-sectional study included 200 health care workers in a tertiary teaching hospital, who were immunized with three complete doses of hepatitis B vaccine. Quantitative determination of anti HBs levels was done by ELISA. The effect of gender, age, smoking, body mass index and duration after immunization on antibody levels were analyzed. Results: The association of anti-HBs status and gender was not statistically significant. Increase in age leads to decline of anti-HBs protective responders. Smoking and higher body mass index are significantly associated with less anti HBs titers (<10 mIU/ml). Conclusion: The highest number of protective responders is seen in initial 5 years post vaccination duration and least protective responders are observed in >10 years post vaccination duration, indicating decline in antibody response over a period of time.

Assessment of immune response to Hepatitis B vaccine by estimation of anti - HBs antibody titer among immunized health care workers