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Objectives: Studyof bacterial flora in perianal region and vagina and relation to neonatal outcome and sepsis. Methodology: After taking detailed history, doing a general physical & obstetric examination and routine antenatal investigations, all the patients were subjected to special investigations. Results: Out of 17 neonatal septic babies 4 babies mother have PROM with significant p value 0.03. 4 mothers have prolonged labor with significant p value 0.03. Out of 17 neonatal septic babies 5 mothers have H/O multiple P/V examination with significant p value 0.04. One patient had history of fever. 10 mothers had Preterm delivery which is statistically not significant p value 0.118. The data were analyzed using the Pearson’s chi square test, macnemar chi square test. Conclusion: From the study it was concluded that there is a certain degree of correspondence between the vaginal and rectal microflora. Microbial colonization of the maternal genital tract is a key factor in most cases of sepsis. Although prevalence study reports a predominance of Gram negative bacilli among female genital colonizers and Gram-negative sepsis among their infants.

Study of bacterial flora in perianal region and vagina and relation to neonatal outcome