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Background: Urogenital infections are the most common gynecological condition constituting about 25% of outpatients. Because of higher recurrence rates and resistance to standard antimicrobials now a days the use of probiotics in augmenting normal bacterial populations is gradually achieving scientific acceptance. Objective: Determine the efficacy of probiotics in treating women with symptomatic white discharge per vagina (WDPV), role of oral probiotics in restoring the vaginal flora. Methods: 70 women aged between 18 to 45 yrs (mean age 35yrs) with symptomatic WDPV who are attending gynecology outpatient procedures, these patients underwent Grams stain, received antibiotics along with probiotics (L. rhamnosus GR-1 and L. fermentum RC-14) for a period of 1 week, again reviewed with repeat Grams stain. Results: Among post-treatment group 46 % of patients showed >30 organisms/100× objective. Fifty percent of patients showed counts between 5 and 30 among post-treatment, but the response in terms of symptomatic relief was about 74%. The improvement in the lactobacilli count was interpreted using Nugents scoring. Conclusion: The combination of probiotic (L. rhamnosus GR-1 and L. fermentum RC-14) is not only safe for daily use in healthy women, but it can reduce colonization of the vagina by potential pathogenic bacteria and yeast.

A study of efficacy of oral probiotics in management of cases with symptomatic white discharge per vagina in a tertiary care hospital