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Objectives: To study the effectiveness, side effects, maternal and perinatal outcome, using low dose Magnesium sulphate and to compare the results with Pritchard regime. Methods: Thirty women with eclampsia aged between 25 to 35 years were prospectively studied over two years at M.G.M hospital & research center, Patna, Bihar. Study was designed into Group A who received low dose magnesium sulphate regime (n=15) and Group B who received standard Pritchard regime (n=15). Results: Groups were compared with respect to type of eclampsia, amount of dose of Magnesium sulphate and Signs of Toxicity of Magnesium sulphate. Magnesium sulphate received was 23gm in Group A and 44 gms in Group B and dose related toxicity was less in Group A. Perinatal morbidity and mortality was higher with Pritchard regime compared to low dose Magnesium sulphate regime. Conclusion: Low dose Magnesium sulphate is as effective as conventional full dose Pritchard regime with lesser side effects with equally good perinatal outcome.

Experience of low dose magnesium Sulphate for the management of Eclampsia and its comparison with Pritchard regime