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Objectives: The present study aims to evaluate the antibacterial activity of Jatropha multifida sap and aqueous extract of Artemisia annua leaves on some clinical strains responsible of urinary tract infection. Methods: The bacterial strains were isolated after the cytobacteriological examination of the collected urine. The agar and liquid diffusion methods were used for the sensitivity test and the determination of the Minimal Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of plant extracts on isolated strains. Findings: Ten bacterial strains isolated from the urine samples were collected. Isolated bacteria exhibited various resistant profiles. As for the antibacterial activity evaluated on the leaves and sap collected, the aqueous extract of the leaves of Artemisia annua had no effect on the strains studied. The MICs and CMBs of Jatropha multifida sap vary according to the bacterial strains studied. Thus, the sap of Jatropha multifida has a bactericidal activity on all strains studied with the exception of the strain of Escherichia coli on which its action is more moderate. At the end of the work, the most isolated bacterial species are respectively Citrobacter freundii (40%), Staphyloccocus aureus (30%) and Klebsiella pneumoniae (20%). All isolated clinical strains are multiresistant. The aqueous extract of Artemisia annua at 600 mg/ml showed no antimicrobial activity on the strains studied. Improvements: The sap of Jatropha multifida shows a bactericidal activity against the various strains tested and could therefore be an alternative to antibiotics following transformations into improved traditional medicines. *Author for correspondence

indian journal of science and technology

Evaluation of the Antibacterial Activity of Jatropha multifida sap and Artemisia annua Extract on some Clinical Strains Responsible of Urinary Tract Infections