English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The aim of the study was to investigate ACTN3 ct-actinin-3 and AMPD1 adenosine monophosphate deaminase polymorphism and genotype combinations in Bulgarian athletes competing in various sports and the relation to peak power output. A mixed group of athletes n = 52 competing at national and international level and a matching genetic control group n = 109 of volunteers were recruited. Participants were genotyped for ACTN3 and AMPD1 by polymerase chain reaction. There were no significant differences in ACTN3 genotype distribution between athletes performing Wingate test 38% RR, 46% RX, 16% XX and controls 41.2% RR, 46% RX, 12.8% XX. AMPD1 distribution was 73% CC, 27% CT, 0% TT and in controls 73.2% CC, 25% CT, 1.8% TT. Athletes performing Wingate test showed equal 33% frequency of RR/CC and RX/CC combination, and 12% RX/CT. Significantly higher P 〈 0.05 peak power output 11.10 W kg1 was found in athletes with RX/CT combination compared to other combinations range 8.83-9.71 W kg-1 and in R-power RR  RX and C-power CC  CT dominant models 9.91 W kgl. Mean power was higher P 〈 0.05 in RX/CT combination 8.93 W kg-1 compared to RR/CC 7.75 W kg-1 and RR/CT 7.95 W kgl. In conclusion, the low frequency of T AMPD1 allele in Bulgarian athletes might indicate that this mutant allele is related to the physical performance. The prevalence of R ACTN3 and C AMPD1 alleles suggests that they could contribute to anaerobic performance. Higher peak power in Wingate test is associated with RX/CT genotype combination and R- and C-power dominant models.

ACTN3 and AMPD1 Polymorphism and Genotype Combinations in Bulgarian Athletes Performing Wingate Test